Lupus nephritis is kidney damage which is a complication of Systemic Lupus
Erythematosus. It is a disease accompanied with obvious manifestations of kidney
damage. So it is the core of treatment to target kidney damage. Stem cell
therapy has good effects on Lupus Nephritis which gives patients chances to get
rid of the condition and improve their life quality.
Stem cells are a group of cells which have the ability to self-renew and
differentiate into cells of any type to repair and replace the worn and damaged
cells. Stem cells can regenerate endothelial cells of blood capillary of
glomeruli and repair glomerular basement membrane to improve the GFR (Glomerular
filtration rate). Stem cells also can obviously improve the symptoms like
hypertention, edema, and changes in urine due to glomerular lesion.
Stem cells are able to differentiate into immune balance cells like Ts cells,
Th cells etc that can remove these factors that can damage tubule, avoid the
further tubule damage and prevent renal failure.
When transplant into body, stem cells will move to kidney with blood and then
they are able to regenerate renal tubular epithelial cells and interstitial
cells, repair damaged renal tubular epithelial cells and interstitial cells due
to bacterium and germ and also enhance physical immunity to prevent renal
failure. Stem cells can recover kidney reabsorption and excretion functions so
that the goal of treating lupus nephritis can be achieved. In many cases, stem
cell transplant has good effects on treating this disease.
Stem Cell Transplant as a brand new technology in medical world is believed
to have the extraordinary promise on treating kidney disease. It is possible to
improve life quality by stem cell transplant. New hope is in near future for
people with Lupus Nephritis.