Acute Renal Failure(AKF) is a rapid loss of kidney function to remove wastes
and concentrate urine without losing electrolytes。 There are numerous causes of
kidney damage including disorders giving rise to clotting within the kidney’s
blood vessels, infections that directly injure the kidney and acute tubular
necrosis etc. It is very important for patients to know about its symptoms and
the ways of diagnosis in order to receive early treatment when diagnosed with
Acute Kidney Failure earlier, which can make sure the good prognosis.
1. The clinical symptoms of Acute Kidney Failure.
People with Acute Kidney Failure usually experience three processes that are
oliguria stage, diuretic stage and recovery stage.
Oliguria stage: Oliguria stage is likely to last for approximately 2-3 days,
sometimes 2-4 weeks for patients with severe condition. Generally, it will last
about 10 days. The longer olgiuria stage is the more severe kidney damage is. At
this stage, the main clinical manifestations are water-sodium retention, edema
(swelling), heart failure and nausea. Even pneumonedema accompanied by
infection, arrhythmia, tendency toward bleeding and narcosis can occur in
patients with more sever AKF. The examination results are Hyperkalemia,
metabolic acidosis and the progressive decline of kidney function.
Diuretic stage: The diuretic stage begins after the oliguric stage has
completed. At the end of oliguria stage, amount of urine begins to gradually
rise which is likely to be 4000-5000ml/d. At this stage, SUN (serum urea
nitrogen) can continuously rise but about one week later it will drop. It is
much easier to develop Hypokalemia, Hyponatremia and dehydration. In addition,
body resistance will drop due to the long-term consuming, which easily gives
rise to overall infection.
Recovery stage: The recovery stage will last for several months to one year.
During this stage, most patients’ kidney function returns to near base-line.
However, a small part of patients will have the viarious level damage of kidney
function. The longer oliguria stage is the more time it takes to recover kidney
function.
2. Exams and Tests
As patients have generalized swelling, doctors may order tests for your
kidney function. The following is related examination which will indicates the
state of kidney function and the causes.
Tests for urine: it includes the color, amount, smell of urine.
Blood test: BUN, Creatinine, Creatinine clearance and metabolic acidosis
should be included to evaluate your condition.
Renal Failure index: RFI=(Creatinine * urine sodium)/ Urine creatinine. The
normal amount of RFI is less than 1.
As for the treatment for AKF, at present, Stem Cell Transplant as the new
breakthrough in medical world has been used to treat the condition. Stem cells
are a class of unspecialized cells that have the ability to self-renew and
differentiate cells desired to repair the kidney intrinsic cells as a result of
which kidney function can recover from damaging.
If you want to know more about Stem Cell Transplant for kidney failure, you
can send us email for details about the newest medical technology. We are glad
to help you. Email: khkpcn@hotmail.com
Hope it is helpful for you and your family!