Hypertension will occur at the 2 or 3 stage of kidney damage. Other clinical
symptoms will occur at the 4 or 5 stage. Here are the symptoms of Diabetic
Nephropathy.
1. Proteinuria: The presence of proteinuria indicates that you are at the 4
stage of Diabetic Nephropathy that is the clinical sign of Diabetic Nephropathy.
At the 2 or 3 stage， the protein may be negative even though persistent
microalbuminuria is present. At the end stage of Diabetic Nephropathy, urine
protein will increase. Within 3-5 years, it will develop into a large amount of
protein urine (Urine protein more than 3.5g/d) which can cause Nephrotic
Syndrome.
2. Edema: Edema will appear together along with urine protein. When
hypoproteinemia occurs caused by the a large amount of proteinuria, colloid
osmotic pressure will drop, which will give rise to the severer edema even
abdominal dropsy and pleural fluid.
3. High blood pressure: High blood pressure is an earlier manifestation of
Diabetic Nephropathy. At the early stage, spasmodic hypertention is the main
symptom. Then it will develop into persistent hypertention. Hypertention will
increase the discharge of urine protein, speed up the progress of kidney decline
that is one factor to promote the kidney function decline.
4. Kidney function damage: The kidney function decline is slow. While
persistent proteinuria occurs, kidney function damage will speed up. Kidney
insufficiency will appear and Serum Creatinine and urea nitrogen will be
elevated. It will develop into renal failure within weeks. Different from
primary glomerulopathy a large amount of proteinuria and nephritic syndrome
still occur in people, which make it more difficult to treating Diabetic
Nephropathy.
As for the treatment, Stem Cell Transplant will be recommended. Stem Cell
Transplant has been used to treat kidney disease and has good effects on
treating Diabetic Nephropathy.
If you have any question about the Diabetic Nephropathy or you are interested
in the stem cell therapy, you can send us email for detailed information. We are
glad to help you. Here is the email: khkpcn@hotmail.com