The Causes and Treatment of Diabetic Nephropathy

The causes of Diabetic Nephropathy
Diabetes is caused by absolute or relative lack of insulin due to the various causes and pathogenesis resulting in metabolism disorders of sugar protein and fat. Diabetes can damage kidneys in many ways which involves in whole kidney structure. Diabetic Nephropathy mostly appears in people who have Diabetes for more than ten years. Protein Urine is the earliest symptom and the exact causes is unknown. Studies show that many factors can give rise to Diabetic Nephropathy. The followings are the main factors.
1. Hyperglycaemia: Onset of Diabetic Nephropathy is closely related to high blood sugar. Poor control of blood sugar will speed up the progress of Diabetic Nephropathy. However, controlling blood sugar well will delay its progressing obviously. Increased productions of high blood sugar and Glycosylation cause masangial cells proliferation, increased extracellular matrix andextended mesenterium.
2. Hereditary factor: People with good control of blood sugar are likely to develop Diabetic Nephropathy. Recently, a study shows that the differences of control and regulate of intercapillary cells is one of factors causing kidney damage. People who have Hypertension family history have more chances of getting Diabetic Nephropathy than people without Hypertension family history.
3. High blood pressure: High blood pressure has no directly linke with onset of Diabetic Nephropathy. But primary Hypertention or blood pressure rising due to Albuminuria will speed up the progress of Diabetic Nephropathy and kidney function decline.
Treatment:
1. Medical treatment: There are three types of treatment in medical treatment. They are diet treatment, medication and antioxidant therapy.
2. Dialysis treatment: People with ESRF have to choose dialysis. However, dialysis can not treat disease fundamentally. It only can remove the toxins in body temporarily.
3. Kidney transplant: Only a small part of people will receive the kidney transplant.
4. Stem Cell Transplant: it is an advanced technology in the world. In many cases, Stem Cell Transplant has been used to treat kidney disease and achieves great effects. Stem Cell Transplant is simple, quick and painless. Above all, stem cells have no side effects. Stem cells capable of self-renewing and differentiating into tissue-cells and organ-cells are able to repair and replace the worn and damaged cells to achieve the goals of treating disease.
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