The Effect of Stem Cell Therapy for Polycystic Kidney Disease

In recent years, with the research development of kidney fibrosis, stem cells enter the body through intravenous injection and directly target at kidney lesions, which can alleviate the condition of hypoxia-ischemia, accelerate the resorption of capsule liquid in renal cyst and inhibit the secretion, through this progress we can realize the goal of shrinking the cyst and then achieve a effective treatment. Meanwhile, the adoption of western medicine and blocking the inflammatory reaction can provide a favorable environment for the action of stem cells. There is no risk to use Stem Cell Therapy and the illness is not likely to relapse.
There is no obvious symptom in the early stage of Polycystic Kidney Disease (PKD), so for most patients, to diagnose the PKD is not easy. The common primary symptoms of PKD are hypertension, hematuria and stomachache, sometimes, urinary tract infection or kidney stone. Any disease has a process of priority order, so does PKD.
PKD means that the whole kidney is covered by the cysts with different size which will grow up with years and press kidney. Thus the construction of kidney will be damaged and the number of nephrons which produce urine will reduce. At last, the damages make kidney hardly maintain the normal function of the body. At this time, late-stage Kidney Failure and Uremia will occur. Exactly, the forming process of Renal Failure, late-stage Renal Failure and Uremia is that of renal fibrosis. The occurrence of them means at least 50% of kidney has been fibrotic.
To eliminate the cysts or control its development early by the stem cell transplant, the occurrence of Renal Insufficiency, late-stage Renal Failure and Uremia. On the one hand, cysts should be controlled and shrank so as to alleviate the pressure to surrounding tissues. On the other hand, the process of kidney fibrosis also should be blocked thus to restore the normal function of damaged tissues. The minimal damage on kidney and the maximum recovery of Renal Function can be achieved. With Stem Cell Transplant, Polycystic Kidney Disease is not likely to relapse; there is a small side effect and no damage to patients’ body. So PKD patients should hold the principle of early diagnosis and the take an effective treatment before kidney function damages.

Stem cells enter patients’ body through direct intravenous injection and target at kidney lesions. And then they will differentiate into cells which are needed by various kidney organs, thus to rebuild the damaged intrinsic cells. In fact, to treat Polycystic Kidney Disease by Stem Cell Transplant is realized by shrinking the cysts, relieving the pressure to surrounding organs and then rebuilding functions of damaged organs, thus to damage the kidney at least extent and rebuild renal function at largest degree. If the cysts can be eliminated and controlled in early stage, patients can avoid the occurrence of Renal Insufficiency, late-stage of Renal Failure and Uremia.

Expert Online