Kidney Failure is also called Renal Insufficiency which is a kind of kidney
disease and described as the decrease of Glomerular Filtration Rate (GFR). It is
typically detected by an elevated serum creatinine level.
Renal Failure can occur from an acute situation or from chronic problems. In
Acute Renal Failure, kidney function is lost rapidly and caused by a variety of
insults to the body. There are three main reasons causing Acute Renal
Failure:
1. A sudden, serious drop of blood flow in kidneys;
2. Damage from some medicines or infections;
3. A sudden blockage that stops urine from flowing out of the kidneys.
Besides the above three main causes, people may also be easy to get this kind
of disease with the following aspects: first, older adults; second, long-term
health problems, like kidney disease, diabetes, hypertension, etc; third, some
accidents, injuries, or complications. All of them can cause Acute Renal
Failure.
As for Chronic Renal Failure (CRF), it develops slowly and initially has a
few symptoms. There are many causes to Chronic Renal Failure. The most common
one is Diabetes Mellitus. In addition, a long-standing and high blood pressure
may also cause this disease. Another well-known reason for Chronic Kidney
Disease (CKD) is Polycystic Kidney Disease which is a kind of genetic disease.
What’s more, CKD is related to chronic glomerulonephritis. It can be divided
into four periods according to the level of creatinine.
1. The reduction of kidney reserve function period. When kidney is in mild or
moderate damage, the normal nephrons can compensatively perform the functions of
those damaged ones. So the urinary function of kidney is normal in general.
2. Renal Insufficiency period. Due to that kidney suffers a further damage,
the reserve function of kidney decreases obviously. So kidney can no longer
maintain a stable environment of human body.
3. Renal Failure period. The endogenous creatinine clearance rate of kidney
falls to 20% to 25% of the normal level. There is a serious nitremia and the
nonprotein nitrogen is more than 60mg.
4. Uremia period. This is the later period of Chronic Renal Failure. The
creatinine clearance rate falls to below 20% of normal level and the nonprotein
nitrogen in blood is no less than 80 to 100mg.
However, how to control Kidney Failure?
Firstly, patients should keep a proper diet. A large number of researches and
clinical practices have confirmed that low-protein and low-phosphorus diet can
slow down the process of Chronic Renal Failure and alleviate the high filtration
condition of CKD.
Secondly, it is suggested that Kidney Failure patients should take Stem Cell
Transplant. Stem cells are a kind of primary cells with the abilities of
differentiation and self-reproduction. They can differentiate into renal cells
and rebuild renal functions instead of the intrinsic cells. Thus, kidney
function will get normal gradually. With this therapy, kidney can be treated
effectively and the renal function will also be restored, achieving the goal of
treating kidney disease and preventing Kidney Failure.