Lupus Nephritis is immunity Damage refers to Systemic Lupus Erythematosus (SLE) combined with bilateral kidney damage. One of the main death reasons of SLE patients is the Kidney Failure. The traditional treatment for Lupus Nephritis makes disease repeat again and again, but the occurrence of stem cell transplantation technology brings new hope to the patient.
The necessary condition of Stem Cell Transplantation treats Lupus Mephritis
1. The pretreatment before transplantation
This is a measure which let the receptor receive extraneous hemopoiesis and reduce the burden of cancer cell; the classical plan is having cyclophosphamide 60 mg/kg for 3 days, and adding 8～12 gray for STBD or FEBI.
2. Receptor and supplier should have the matching human HLA system
It exists in sixth pair of chromosome, doctor call this HLA-A，B，C,DR locus, ，HLA—DR locus related to whether transplantation can success, they must be match. In this way, it has high success chance and low risk.
3. Need a certain amount of hematopoietic number
This is not difficult to understand, since as seed cell, it will go to the new “soil” environment to take root, sprout, bloom and bear fruit, it is not a smooth sailing. In the process will be lost some stem cells, and can’t work without a certain quantity of stem cell.
The process of Stem Cell Transplantation treats Lupus Nephritis
First let largely hemopoiesis of marrow are released into blood; this process is called “mobilization”. Then through the blood cells centrifuges separate a lot of blood for transplantation, this is called “peripheral blood transplantation”. At present, people who donate marrow don’t need to extract marrow, just “donate blood”. Furthermore, with the development of technology, now using the technology of hemopoiesis “mobilization”, only need gather 50-200ml separated peripheral blood for getting a sufficient number of hemopoiesis. After gathering enough hemopoiesis, the blood can go back to the patient’s body.
The effect of Stem Cell Transplantation treats Lupus Nephritis
The treatment of Stem Cell Transplantation for Lupus Nephritis doesn’t have any side effect, because Stem Cell Transplantation has the function of rebuilding the damaged immune system, so the treatment of Stem Cell Transplantation for Lupus Nephritis can make patient avoid disease relapse, then achieve the purpose of treating Lupus Nephritis fundamentally.
A lot of clinical research has proved that the treatment of Stem Cell Transplantation for Lupus Nephritis has effective effect, which blocks renal fibrosis fundamentally, and repair the function of damaged renal cell; this is the best method to treat Lupus Nephritis. For more information, please Email us at khkpcn@hotmail.com