The Symptoms of Diabetic Nephropathy in Different Stages

Clinically, Diabetic Nephropathy can be divided into five stages, and patients have different symptoms in these five stages. Now this article will give some detailed introductions about them.
★Stage 1
This stage featured by large renal volume which enlarge by 25%, this can be seen by B ultrasound. The glomerular filtration rate (GFR) rises, exceeding 120ml/min and even reaching 150ml/min which is equal to that of blood sugar. Renal biopsy shows no abnormality and blood pressure keeps normal. Due to that it is the early stage of Diabetes, these symptoms can recover to a normal level under the circumstances of strict controlling blood sugar and receiving insulin therapy for several weeks to several months.
★ Stage 2
In this stage, the excretion of albiduria protein shows no increase when the patient is at rest, but after exercise, the excretion will increase. For example, if the patient rides a bicycle, which makes his heart rate reach 75% of the highest heart rate of his peers, for 20 minutes, the one-hour excretion of albiduria protein can exceed 20 MCG/min and the glomerular filtration rate can recover to the normal level. If the filtration rate keeps high, that means patients are in the period of high risk of Diabetic Nephropathy, and the illness condition can be reserved.
★ Stage 3
In terms of early Diabetic Nephropathy, the continuous urinary protein transformed from post-exercise albiduria protein increases up to 20---200 MCG/min and the glomerular filtration rate maintain normal. In the late stage, the blood pressure may slightly increase and if patients do not take some effective treatment measures, 90% of them will suffer from serious Diabetic Nephropathy.
★ Stage 4
It is the stage of distinct Diabetic Nephropathy (or the stage of clinical Diabetic Nephropathy). In this stage, continuous urine protein occurs and the ration of urinary protein exceeds 0.5g/24h which equals that the excretion rate of albiduria protein exceeds 200MCG/min. And the glomerular filtration rate decreses accompanied with Hypertension. If the blood pressure can not get under good control, the glemerular filtration rate will decrease at an average speed of 1---1.22ml per month and deteriorate constantly, and patients will suffer from late Renal Failure within 5 to 8 years.
★Stage 5

It is the late stage of Diabetic Nephropathy. In this stage, the blood pressure goes up dramatically, urine protein decreases and the glomerular filtration rate can drop below 10ml/min. At the same time, Urea nitrogen and creatinine rise, Edema and Hypertension further aggravate and Hypoproteinemia occurs. Diabetic Rtinopathy and Diabetic Neuropathy always presented in this stage too. To learn more information, please Email us at khkpcn@hotmail.com

The Effect of Stem Cell Treatment for Nephrotic Syndrome

The western often use a large amount of hormone to treat Nephrotic Syndrome with a quick temporary effect. But the patients with Nephrotic Syndrome often have a repeated outbreak, and they suffered a lot untold pain. The patients didn’t see the hope until the emergence of stem cells in Regenerative Medicine. The treatment of stem cells for Nephrotic Syndrome is a method which can fundamentally repair the damaged kidney cells and rebuild renal function. Why did we say that Stem Cell Transplant can treat Nephrotic Syndrome?
Nephrotic Syndrome is a syndrome caused by the increasing of permeability of glomerular filtration membrane, and a large number of plasma proteins which run away from urine. The main reason for the disease is the inflammatory reaction caused by several of infections. A large number of immune complexes formed in blood will deposit in the glomerular epithelial cells and basement membrane, and thus the normal function of the glomerular is damaged. As a result, proteins and other macromolecules will be discharged with urine.
Stem cells are extracted from different organs of the human body, and then inputed into patients’ body after culture and differentiation. With the function of self-replication and multi-differentiation, stem cells repair damaged cells and restore damaged organs, thereby restoring the normal renal function.
Stem cells have a significant effect for Nephrotic Syndrome patients who have received long-time treatment, but the illness condition can’t controlled well and proteinuria occurred repeatedly. ShiJiazhuang Stem Cell Center can make the most appropriate therapeutic schedule for different patients in different stages. Furthermore, countless patients get rid of/ relieve the pain by our effort successfully.
1. Compared with traditional therapy, Stem Cell Transplant has an unparalleled advantage in treating Nephrotic Syndrome.
The source is convenient. Stem cells are easy to separate, culture, amplify and purify. After several times generation, they still have the features of original stem cells.
2. Low immunogenicity. Stem cells in the original state cannot be easily identified. They don’t have immune rejection characteristic and blood type matching problems.
3. The biological characteristics won’t be changed with the long-term generation. They can differentiate into renal cells, muscle cells, liver cells, bone and cartilage cells and some other kinds of cells.
4. Homing feature. The injury signals can stimulate stem cells to make the migration to the damaged tissues and organs, and then differentiate into new renal cells. It can move to the renal lesion automatically through the function of homing, and repair the damaged cells fundamentally.

Stem Cell Transplant open a promising door for Nephrotic Syndrome patients, greatly improve the patients’ quality of life, bring new hope for their future. To learn more information, please Email us at khkpcn@hotmail.com

Which Treatment Has Better Effect for Diabetic Nephropathy

Diabetic Nephropathy is a complication of DMIP which is caused by Diabetes. Renal function can by reversed by proper treatment in the early stage of Diabetic Nephropathy. If Diabetic Nephropathy develop into Renal Failure or Uremia, this treatment will spend more time, money, and worst of all, the disease can’t be cured. Therefore, it is very important to choose a proper treatment in the early stage of Diabetic Nephropathy.

Firstly, we need to understand the stages of Diabetic Nephropathy. That is because different stage has different treatment.

1. Glomerular filtration stage: it is featured by increasing glomerular filtration rate and enlarging the size of kidney. These changes accompany with high blood sugar. With the help of insulin treatment, the disease can be reversed in this stage, but can’t recover completely.

2. Kidney damage stage without any symptoms: this stage is featured by normal proteinuria discharge rate and changed glomerular structure.

3. The early stage of Diabetic Nephropathy: the discharge rate of albumin is 20--200μg/ min, patients present a slightly increased blood pressure and glomerulus begin to necrosis.

4. This stage is featured by a lot of albuminuria(>3.5g everyday),edema and high blood pressure. Diuretic medicines have little effect for patient’s edema in this stage.

5. The late/end stage of renal failure: because glomerular basement membrane become more and more thick, blood capillary become more and more narrow, more and more glomeruli begin to necrosis/ sclerosis. In the end, the filtration function decrease gradually, which leads to Renal Failure.

Different period should choose different treatment.

Normally, the best treatment for the front three periods is Micro-Chinese Medicine Osmotherapy. The main therapeutic principle for Micro-Chinese Medicine is to promote blood circulation by removing blood stasis, repair the damaged cells. Clinical practice has proved that urine protein can be reduced by Micro-Chinese Medicine; meanwhile, renal function can be protected by Micro-Chinese Medicine in the early period of Diabetic Nephropathy. Furthermore, the hyperplasia of glomerular extracellular matrix can be alleviated and hardeningratio of glomerulus can be reduced.
The main function of Micro-Chinese Medicine is to promote blood circulation, remove the stasis in channels. The main pathological change of Diabetic Nephropathy is glomerulosclerosis and basement membrane damage. After superfinely shattered, the active substance can aim at expand all arteries and increase the effective blood perfusion, increase the oxygen supply of damaged glomerulus, thus improving the micro-blood circulation, promoting metabolism, alleviating and restoring the sclerosis states of glomerulus.
The best treatment for patients who in the later stage of Diabetic Nephropathy is dialysis+ Stem Cells Transplant.

In the later stage of Diabetic Nephropathy, kidney transplant can be utilized for patients, but it is not easy for general family to afford the high cost of kidney transplant. The best therapeutic method is to utilize stem cells for repairing the damaged renal cells when dialysis is maintaining the life, then stem cells can generate new nephrons to replace the dead/ anile cells, thus rebuilding the renal function, prolonging the time interval of dialysis, even let patients get rid of dialysis. For more information, please Email us at khkpcn@hotmail.com

Diabetic Kidney Disease in Elderly People

Nowadays, Diabetes has become a very common disease which elderly people easily suffer from, and Diabetic Nephropathy is the most horrible complication of Diabetes because it can pose a certain threat to patients’ lives. So we should know something about how to treat Diabetic Kidney Disease in a proper way.
With the increase of age, various organs of elderly people are experiencing atrophy and decreased functions. Aged people are not sensitive to all kinds of stimulus, and their poor tolerance to glucose together with the resistance of insulin against external environment, which lead to the decrease of sugar tolerance, thus driving up the level of blood sugar. Elderly Diabetic patients always present abnormality of lipid metabolism, such as high triglyceride, high cholesterol, low-density lipoprotein hyperlipidemia, etc. In addition, Diabetic of elderly people is always accompanying with infections, respiratory system has the highest infection rate, and then urinary tract infection follows. The treatment of Diabetic Kidney Disease should be taken according to the specific conditions.
By Micro-Chinese Medicine Osmotherapy, the prescriptions of Chinese medicine are finely shattered into tinier grains, which make the effective medicines fully release, thus improving the penetrability of Chinese medicine. Then, the medicines will rapidly permeate into renal lesions, combine with immune complexes in the kidney and change their valence bone structure, and the immune complexes will be smashed, decomposed and excreted out of the body at last. This process will effectively enhance the repairing of glomerulus, make the function of glomerulus gradually recover and ease renal dysfunctions caused by arteriolonephrosclerosis which is resulted by increased blood pressure. And eventually, the symptoms of proteinuria and microscopic hematuria will get eased and Renal Failure can also be prevented.
In the respect of diet, according to the distinct symptoms of ‘three high and one low’ (massive proteinuria, Edema, Hyperlipidemia and Hypoproteinemia), patients should take low-salt and low-fat foods and high-quality protein to recuperate their kidneys. At the same time, they should also receive treatments of dialysis and anti-inflammation and for patients who have severe condition, they should supplement blood and calcium, which can correct acid and electrolyte imbalance, and control blood sugar, promote urine and eliminate Edema. When receiving Micro-Chinese Medicine Osmotherapy, patients should also take relevant Chinese medicine liquids to treat from both internal to external, thus making the medicine play its function to the most, which will gradually block the disease’s development towards Renal Failure or Uremia fundamentally.

For elderly people, they should take timely treatments and choose a suitable therapy. We hope that people can pay more attention to the health of the elderly and if some diseases are detected, we must take measures to treat as early as possible. For more information, please Email us at khkpcn@hotmail.com

Different Stages of PKD and Its Treatment

Polycystic Kidney Disease, as a congenital disease, has regularity in its development. We conclude from statistics that there are five different periods when PKD develops.

1. Emergence Period
PKD is a congenital disease. Usually, once a child is born, he or she has already carried the cyst which is comparatively small and difficult to be observed. Generally, patients can hardly find they have PKD before their twenties. And the person who has relatives with PKD should have physical examination as early as possible to check if they have the same disease. If the answer is ‘Yes’, close observation and elaborate nursing care is needed.

2. Growth Period
This period has the feature of rapid growth, usually in the sufferer’s thirties or forties. In medical community, this period is called Growth Period. Intensive observation is necessary in this stage because of the high-speed development of those cysts. So far, Western Medicine community is incapable of treating the root cause of PKD in growth period. The treatment which seems passive can only treat symptoms like hypertension. By comparison, Traditional Chinese Medical Treatment that aims to promote blood circulation and remove blood stasis is preferable, because it can achieve the goal of stopping or delaying the growth of those cysts, prolonging the sufferers’ lifetime. All in all, this is a critical period for Traditional Chinese Medicine to delay the growth of cysts through promoting blood circulation and removing blood stasis.

3. Tumefaction period
Cysts are growing further after sufferers enter their forties. This period is called Tumefaction Period lasting from the time when the cyst is more than 4 cm in diameter to the start of Ulceration Period. With the expansion of those cysts, such symptoms as osphyalgia, proteinuria, hematuresis and elevation of blood pressure etc. appear. It is considered as the critical period to use Chinese and Western combined treatment. Doctors can adopt traditional Chinese Medicine to promote blood circulation and remove blood stasis, thus achieve the goal of protecting renal function.

4. Ulceration Period
In this period, cysts can fracture due to external cause if the cysts keep growing. Sufferers should be hospitalized immediately after fracturing, to actively control infection and prevent septicemia from happening, thus create a favorable therapeutic environment for follow-up medical treatment.

5. Uremia Period
In this period, treatment is targeted on treating Uremia so as to achieve the goal of actively protecting remaining renal function. At this point, peritoneal dialysis or hemodialysis may be needed. For more information, please Email us at

khkpcn@hotmail.com

Serum Creatinine is 2.83 with IgA Nephropathy How to Cure

This is Catherine from Kidney Disease Hospital in China .Just now we got your inquiry about serume creatinine is 2.83 with IgA Nephropathy. And now your higher creatinine levle has been a sign of your kidney damage. You know creatinine is a metabolic disease of the muscle . And normally it can be cleared out our body by urine . And you know our kidney is responsible for clearing the toxicity and waste out of our body . But now as the immune abnormal reaction of your body when the outside invaders such as the (infection, toxicity, virus etc) your kidney will have the inflammatory reaction .
And now according to your condition yours is the Chronic glomerular nephritis. And some of your cells in the kidney are in the inflammatory reaction stage .So now you still have a great chance for the treatment as as long as we can limit the inflammatory reaction and your condition can be much better and as long as your kidney 's futher damage has been stopped and your kidney function will improve. At that moment your creatinine will become lower .
Now you have been in the stage 3 of your Chronic Kidney Disease. And the early treatment can help you avoid dialysis and future transplant . As for the daily care you should pay attention to your diet and your health life style . But these can only do a limited help for your condition. In order to have your disease treated from the root the systematic treatment is still needed Clear ?
You'd better do a urine test to see if there is much protein in your urine . Besides what is your hemoglobin levle now ? And have you done the ultrasound test ? what is the size of your kidneys ?

Take care and if you have any question pls Email us at khkpcn@hotmail.com

I Have Parapelvic Cyst in My Left Kdney Is There Any Alternative Medicines

So sorry to reply you, This is Jane from kidney disease hospital in China, i have read your information arout your kidney disease conditions, the timely treatment is so necessory, i know you must have pain in back, right?

For similar cases. our Micro Chinese medicine therapy First, i think i need to explain our Micro Chinese Medicine Therapy, which contains seven kind of Chinese Medicine Theraphy:

medicnine clyster,medicnine circle treatment,medicine Oral medicine, Chinese medicine bath, Chinese medicine foot bath.Chinses medicine moxibustion. these treatment therapys combined to treating the kidney disease, repair damaged kidneys. Chinese herbal helps promote the blood circulation of blood vessels all over the body. Some special herbs help to deal with the damaged renal tiny blood vessels. With the renal blood circulation, the oxygen and blood will be carried to damaged kidney vessels and tissues, repairing the damaged kidneys and improve kidney function.


Do not concern the curative effect of the Micro Chinese medicine therapy, it can must have a great effect , do believe us. To learn more information, please Email us at khkpcn@hotmail.com

Diet for CKD with Creatinine 6.5, Blood in Urine and Proteinuria ++

Could you please tell diet for CKD with creatinine 6.5, blood in urine and proteinuria ++?
Frankly spaeking, the high creatinine level indicates serious kidney function decline. Anyway, hope you can reply me with more information on your overall kidney condition, I will have your condition analyzed and see what we can do for your case.
Our suggestions for your dietary arrangement are as below:
1. Limit the salt intake.(you are hbp patient, if you dont have swelling 3g everyday)
2 High quality protein food: such as fish, chicken, milk, egg white, etc(that is good for her conditon). Limit plant protein as they are not easy to be absorbed, such as bean curd, soy-bean milk and soy products(don’t eat)
3. Should pay attention to high calcium low phosphorus: for kidney disease, phosphorus and calcium are easy to be disordered, for that case, pay attention on high calcium and low phosphorus foods is necessary: usually high calcium things often also high phosphorus such like animal organs, ribs, and shrimp skin and so on.s(don’t eat)
4. Forbidden of stimulating effect foods, such as mustard, onion, ginger, garlic, chili, alcohol drinks, coffee, please avoid strong tea, and green tea is okay, no smoking.5. Limit potassium food such as rape, spinach, leek, tomato, kelp, banana, peach, etc.
6. Limit fat intake: the proposal with olive oil, peanut oil cooking are good choice.
7.Vitamin supplements: it can maintain the metabolization balance of human body: more vegetables and fruits, such as,apples, pears cucumber, papaya, etc, but eating fruit and vegetables should pay attention to avoid high potassium ones.

but , as a doctor i need to say that your creatinine is 6.5, bad news. just no food that is not enough. i think you know your condition well, your creatinine is uptrend...right? To learn more informaiton, please Email us at khkpcn@hotmail.com 

Can IgA Nephritis be Treated by Western Medicine

Clinically, IGA Nephritis is one of the most common disease in China. At present, the treatment for it is mainly categorized into traditional Chinese medicine method and western medicine method. Numerous patients have used western medicine method. How on earth are the therapeutic effects of western medicine treatment for IgA Nephritis? This question is most concerned by patients. The detailed introduction is as following:
First of all, we will introduce western medicines commonly used for the treatment of IgA Nephritis in clinic. They are mainly divided into the following categories:
1. Immunosuppressant:
Immunosuppressant can profitably control the clinical complications in a short term and make a temporary control for the inflammation response of kidney tissues.
2.Anticoagulation, anti-platelet aggregation drugs:
This kind of medicine can resist the abnormal blood clots in the glomerular and reduce the platelet aggregation so as to slow the formation of blood clots inside the glomerular. It also has certain effect on the anticoagulation and the suppression of blood clots’ composition. These medicines contain dipyridamole, warfarin, LMWH and urokinase.
3. ACEI (angiotensin converting enzyme inhibitor) and angiotensin receptor antagonist:
These two kinds of medicine can inhibit angiotensin, relieve the hypertension caused by the kidney damage and positively maintain patients’ blood pressure in a certain range in the short term.
4. Glucosidorum Tripterygll Totorum
This medicine is mainly adopted for the patients with IgA Nephropathy who are complicated by proteinuria and hematuria. After the urine protein turn to be negative, this medicine can be stopped. Meanwhile, the Chinese medicine treatment should be prolonged in order to protect and repair the damaged renal tissues. By this, the urine protein can turn to be negative completely and proteinuria won’t relapse, even encountering the inducing factors again.
5. Hormone
Prednisone and methylprednisolone can treat the complications such as proteinuria. The shock therapy of methylprednisolone has a better therapeutic effect on the IgA Nephritis with plenty of proteinuria and rapid deterioration of renal function.
How are the therapeutic effects of western medicine for IgA Nephritis?
Generally speaking, the long-term use of above drugs can bring many side-effects to the patients. In addition, it also influence other organs in the body. There is no doubt that a proper use of hormone can reduce its side-effects, but there are also such situations, like insufficient dosage or too much in the beginning, nonstandard in the process of reducing and so on, in which the impacts of hormone to patients are the damage to illness condition, instead of just being counterproductive.
So, more and more IgA Nephritis patients began to look for traditional Chinese medicine therapy, abandoning the treatment of hormone and western medicine.

The Micro-Chinese Medicine Osmotherapy put forward by renal fibrosis theory can block patients’ process of renal fibrosis foundamentaly, repair damaged kidney inherent cells, restrain inflammatory reaction and restore damaged kidney original structure thus to treat the disease scientifically and effectively. This treatment method has been recognized by more and more patients because of its good therapeutic effects. For more information, please Email us at khkpcn@hotmail.com

What are Complications of Hypertensive Kidney Disease

For many Hypertensive Kidney Disease patients, their treatments are always delayed due to their poor understandings of the symptoms of the disease. The complications of late Hypertensive Kidney Disease include Heart Disease, Uremia and others. The following is the introduction:
Angina, Myocardial Infarction and Heat Failure
The muscle strength increases which drives up the myocardial consumption of oxygen. If Coronary Artery Atherosclerosis occurs too, the reservation function of coronary artery blood flow will decrease and the cardiac muscle will provide less oxygen, which will result in Angina, Myocardial Infarction and Heart Failure.
Renal Arteriosclerosis and Uremia
Hypertension accompanied by Renal Failure accounts for 10% of the complications of Hypertensive Nephropathy. Hypertension is closely related to kidney: on one hand, Hypertension causes the damage of kidney; on the other hand, the deterioration of renal damage can aggravate Hypertension. Hypertension and renal failure can affect each other, leading to a vicious cycle. The abrupt development of Hypertension can result in massive diffuse lesions of renal arteriole and malignant renal arteriosclerosis, which can develop into Uremia quickly.
1. Cerebrovascular Accident
It is also called Apoplexy with the characteristics of rapid deterioration and high fatality rate. It is the most ferocious one among acute cerebrovascular diseases. The higher the blood pressure of Hypertension patients goes, the higher the incidence of Apoplexy will become. Once the Hypertension sufferers present dizziness, headache, nausea, numbness, weakness and other symptoms due to their overexertion, anger and rage, they should put emphasis on the possibility of suffering from Apoplexy. If it happens, the patient should go to hospitals for examinations.
2. Coronary Disease
The change of blood pressure can cause the imbalance between oxygen supply and oxygen demand of myocardium. If the blood pressure of Hypertension patients keeps going up, the left ventricular afterload and the arterial pressure of Hypertensive Heart Disease will increase, which can bring more burden to the heart and result in Compensatory Left Ventricular Hypertrophy. When Hypertension is accompanied by Left Ventricular Hypertrophy, it develops into Hypertensive Heart Disease which will finally lead to Heart Failure.

For more information, please Email us at khkpcn@hotmail.com

The Early Symptoms of Nephrotic Syndrome

Clinically, the experts from Shijiazhuang Kidney Disease Hospital believe that there are four main features of Nephrotic Syndrome: massive Proteinuria, Hypoproteinemia, Hypercholesterolemia and Edema in the whole body.
1. Massive proteinuria.
It is the symbol of Nephrotic Syndrome. It mainly includes albumin and other plasma protein elements as well. The permeability change of glemerular basement membrane is the fundamental cause of proteinuria, in addition, the change of charge barrier and mechanical barrier (the barrier of glomerular capillary aperture) and the ability of reabsorption and catabolism of renal tubular epithelial cells can also affect the forming of proteinuria. Glomerular filtration rate, the concentration of plasma protein and the protein intake can directly affect the degree of proteinuria. When glomerular filtration decreases, the proteinuria will decrease; when severe Hypoproteinemia occurs, the excretion of urine protein will rise and the high-protein diet can also drive it up. Thus, it is improper and inexact to diagnose the degree of proteinuria only by testing the quantity like protein every day, so to judge it, some further examinations of albumin clearance rate and urine protein/creatinine (>3.5 means proteinuria within the scale of kidney disease) should be done.
2. Hypoproteinemia
It is the second characteristic of Nephrotic Syndrome. It means that the concentration of serum albumin is under 30g/L. When someone suffers from Nephrotic Syndrome, their livers will compound more albumins, and when the food includes enough protein and calories, their livers will roughly compound 22.6g of albumin per day which is much more than 15.6g of ordinary people. When the albumin compounded by liver can not make up the loss of urine protein, Hypoproteinemia will occur.
Patients with Nephrotic Syndrome always have negative nitrogen balance, and when high protein is loaded, the negative nitrogen balance can be converted into positive. Loaded high protein may make the excretion of urine protein go up due to the increase of filtered protein of glomerulus, so the increase of plasma protein concentration is not obvious and meanwhile taking angiotensin-converting enzyme inhibitors can inhibit the excretion of urine protein, which can lead to the distinct growth of blood albumin concentration.
There is one thing which should be emphasized, that is when Hypoproteinemia occurs, the combination of medicine and albumin will decrease and the concentration of free medicine in blood will go up, which may result in the toxic reaction of the medicine.
3. Hyperlipidemia
In the case of Hyperlipidemia, the total cholesterol and triglycerides increase obviously, and the level of Low-Density Lipoprotein and Very-Low-Density Lipoprotein will increase too. Hyperlipidemia is closely related to Hypoalbuminemia, and LDL/HLDL increase only when the concentration of serum albumin drops under 10—20g/L while High-Density Lipoprotein keeps normal or decreases. The increase of LDL/HDL will increase the risk of Arteriosclerosis. Hyperlipidemia patients present lipid urine with double-refraction fat bodies, which may be epithelial cells or fat-body casts that including cholesterol.
4. Edema

For patients, the most notable symptom is the worsening Anasarca. At the beginning, swelling can occur in eyelids, face and ankles in the morning. With the development of the disease, swelling will spread to the whole body, together with the occurrence of Pleural Effusion, Ascites, Pericardial Effusion, Mediastinal Effusion, swelling in scrotum or labia and sometimes Pulmonary Edema appears as well. Patients with severe Edema can hardly open their eyes and their heads and necks will become thicker together with waxy-pale skin, hydrothorax and ascites, as a result, they suffer from difficult breathing and they can only keep sitting up. The degree of severity is related to Hypoalbuminemia, which is possitive correlation. For more information, please Email us at khkpcn@hotmail.com

How to Treat IgA Nephropathy by Micro-Chinese Medicine Osmotherapy

Some people (children in particular) may present gross hematuria after they get Infection in the Upper Respiratory Tract or Acute Gastroenteritis or Urinary Tract, and the spacing interval is from 24 hours to 72 hours. Gross hematuria can last for several hours to several days and then turn into persistent microscopic hematuria, hematuria maybe disappear gradually, but attack frequently, even develop into gross hematuria which accompanying with slight symptoms like sore muscle, Dysuria, pain in waist bone, or suddenly increase of blood pressure or urea nitrogen. This is the early symptoms of IgA Nephropathy. What is IgA Nephropathy?
Let’s start from the concept if you want to deeply explore IgA Nephropathy. IgA is a sort of immunoglobulin, which belongs to a kind of human antibody. According to the immune function, it can be divided into serotype and secretion. Serotype IgA exists in serum and accounts for 85% of the total IgA. Secretion IgA exists in secretion fluid which covering the mucosal surface of nose, pharynx, trachea, intestines and bladder, and it can inhibit the adhesion of microbes on respiratory epithelium and slow down the propagation of virus, in addition, it acts as a mucosal barrier with antibody activity against certain virus, bacteria and ordinary antigen, and also it is the first defense line to prevent pathogen entering the body. Under abnormal circumstances, when the kidney is stimulated by various inflammations, IgA will excessively deposit at mesangial area and other region, combine with antigen and then produce immune complexes, which can result in pathological damage of renal structure and cause a series of clinical manifestations. That is IgA Nephropathy.
Why do people suffer from this disease?
The reason why patients suffer from this disease is that immunologic function deficiency in mucosa, Within a certain period of time, if the immunity decreases and meanwhile the mucosa of upper respiratory tract or gastrointestinal tract get infections, thus bacteria or virus invade human body that make the abnormal structure of IgA have antigenicity, then combine with autoantibody for forming antigen-antibody complex of IgA. These complexes deposit under the mesangial cells of glomerular capillary, which lead to the impairment of physiological function of mesangial cells. So we call this disease as IgA –based hyperplasia of mesangial cells.
How to treat this disease?
Clinically, the conventional treatment is anti-inflammation combined with hemostatic medicine for stopping hematuria. But they forget one thing that is the root of this disease---- the normal physiological functions of mesangial cells are impaired. Only figure out the root of this disease, all problem can be solved.
In the process of treating this disease, the therapeutic effect should obtain through the following methods, no matter Chinese Medicine or Western Medicine or Chinese Medicine combined with Western Medicine.
1. Dilating blood vessels. Why? Because after the stimulation of IgA immune complex, the mesangial cells of renal capillary lack of blood and oxygen, and the aim of dilating blood vessels is to improve renal blood circulation and ease the state of lacking blood and oxygen of various renal intrinsic cells, creating a favorable environment for the repair of mesangial cells.
2. Anti-inflammation. Why? It is easy to understand. Anti-inflammation is to reduce the infiltration of inflammatory cells and ease repeated impairment of glomerular mesangial cells.
3. Anticoagulation. The growth of inflammatory cells in blood will increase blood viscosity to a certain degree, which can urge the forming of thrombus in glomerular capillary. The application of anticoagulation medicine is to end the forming of micro-thrombus and maintain unobstructed blood flow, thus paying a solid foundation for the further repair of mesangial cells.
4. Degradation. The increase of inflammatory cells in glomerular capillary and the micro-thrombus in blood vessels together with the sedimentation of IgA immune complex will lead to the gathering of sediments of glomerular capillary mesangiall cells and the increase of extracellular matrixes. To ease these symptoms, patients have to take relevant medicines to continuously degrade the deposited extracellular matrixes and make them excreted from the body through urine, thus avoiding the hardening of glomerulus. For more information, please Email us at khkpcn@hotmail.com

Hepatitis B Virus-associated with Glomerulonephritis

The morbidity of Glomerulonephritis which is accompanying with Hepatitis B Virus is about 6.8%~20.0%, and this disease is more common in Children. What are the early symptoms of Hepatitis B Virus-associated with Glomerulonephritis?
1. This disease often occurs among children and young people, especially for young man. There are many kinds of clinical manifestations like Nephrotic Syndrome, Simple Proteinuria, Hematuria and Protein etc. Nephrotic Syndrome are very common in children, patients with serious condition will present Acute Nephritic Syndrome and Renal Failure.
2. The symptoms in kidney. All patients with Hepatitis B Virus-associated Glomerulonephritis show the symptom of hematuria or proteinuria. Because the onset of Hepatitis B Virus-associated Glomerulonephritis conceal, more diseases are checked in the urine test and occur as Nephritic Syndrome, at the same time, patients present different level of edema and ascetic fluid.
3. Symptoms in livers. Some patients can present the symptoms of liver enlargement or dysfunction of liver function. During the attack of hepatitis, patients can present asymptomatic protein, microscopic hematuria and syndrome of serum sickness. The proteinuria fluctuates from severity to mildness.
4. Microscopic hematuria lasts for a period after the proteinuria become negative. Some patients may have paroxysmal gross hematuria. Usually, there is no obvious edema and oliguria. Hypertension often occurs among patients with Membranoproliferative Glomerulonephritis.

These are the early main symptoms of Glomerulonephritis which is accompanying with Hepatitis B Virus. But different people may have different symptoms except for these main symptoms. If you want to know more about it, please feel free to contact us online or Email us at khkpcn@hotmail.com

The Symptoms of Early Renal Failure

Renal Failure is in the middle or later period of renal fibrosis. In that period, the patient’s kidney has been severely impaired and if effective treatments are not taken, the disease will continue to deteriorate and eventually develop into Uremia. What are the symptoms of renal failure in the early period? Now, we will give you some introductions.
1. Feeling sleepy and weak is the most common symptom of early renal failure.
This is probably a manifestation existing for a long time, while being ignored very easily because there are so many causes which can result in fatigue. For many office workers, long-term and intense brainwork, disordered life route and excessive fatigue always lead to their renal failure.
2. Swelling is the most visual symptom.
This is an obvious symptom. The kidney is unable to eliminate the excessive moisture in the body making the fluid stranded in the tissue space. At the beginning, the swelling only occurs at ankle and eyelid and fades away after rests. But if the swelling is continuous and arising at the whole body, it proves the patient is in very serious situation.
3. Functional disorder of digestive tract and poor appetite caused by increased serum creatinine and the accumulation of toxin in the body.
It is caused by the poor digestive function affected by the retention of urotoxin. Most people take it for granted and let it develop without control. Later, these symptoms such as abdominal swelling and discomfort, nausea and vomit will arise and then result in increased defecation or mashy excrement. At that time, the disease becomes severe and that’s why the patient has to go to hospital for treatment.
4. Hypertension will appear in the early stage of renal failure.
The kidney has the function of expelling sodium and moisture. If the kidney’s function is impaired, sodium and moisture will be stored up in the body and the kidney will secrete some substances driving the blood pressure up. As a result, in the early stage of renal failure, patients will suffer from hypertension of different degrees. And if there is hypertension together with different blood clotting mechanisms, it may lead to nose or gum bleeding, which should arouse the patients’ attention.
5. Sallow complexion caused by renal anemia.
It is caused by anemia and because the attack and expansion of this manifestation are very slow, it won’t have obvious contrast in a short time just like that you can hardly see any significant difference of one’s complexion in a day.
6. Urine output changes caused by the degeneration of renal function.
With the degeneration of kidney’s filtration function, some patients’ urine output will gradually become less as the disease develops. Even if the urine output keeps normal, since the toxin in urine becomes less and excessive waste can not get out of the body, as a result, the urine output can not reflect the real situation of renal function.

A good understanding of the early symptoms of renal failure can help you with the treatment. If you have the above symptoms, please turn to doctors for help as soon as possible in order to avoid deterioration of the disease and the occurrence of Uremia. For more information, please Email us at khkpcn@hotmail.com 

What Causes End Stage Renal Disease (ESRD) and How to Prevent It

What causes End Stage Renal Disease (ESRD) ? Many people know that Uremia is an awful disease and it is the final period of kidney disease. People always call ESRD deathless cancer because it is extraordinarily difficult to cure it. Patients with severe Uremia can only sustain their lives through receiving dialysis.

What are the causes of ESRD and how to prevent it?

1. 30% of the Diabetes can directly develop into ESRD Diabetes. Recent statistics show that in China, there are 43.2 million patients with Diabetes and 50.64 million patients with decreased sugar tolerance. That is to say that there are 13 million Uremia patients and more than 15 million Uremia high-risk people in China with Diabetes as the only cause.
2. 15% of the patients with Hypertension will directly develop into ESRD sufferers. According to China’s statistics in 1998, the Hypertension patients account for 10% of the total population which means that there is one Hypertension sufferer in every 10 people, among whom one and a half people will become Uremia patients.
3. Caused by urinary system infection or urinary tract infection. According to the statistical data, in China the incidence of urinary infection is 0.23% for men and 2.37% for women. Men and women, the old and the young all can suffer this disease especially the married women in childbearing age. In our country, chronic Pyelonephritis is the second biggest reason for Uremia, taking up 21.2% of the total number.
4. Kidney disease is the main cause of ESRD and all the chronic kidney diseases will eventually develop into Uremia. Among them, chronic nephritis is the top reason and in the diseases resulting in Uremia, chronic glomerulonephritis accounts for 55.7% of them.
5. Related to age. The old people in China accounts for 10% of the total population and by 2025, the proportion of elderly people above 60 among the total population will reach 19.3%. The physical examinations show that 17.3% of the elderly suffer from different renal diseases and among the patients in hospital, the old with urinary system diseases takes up 3.4%---6.3% of them. It is the eighth cause of death of the old patients in hospital.
6. Caused by drugs’ toxic side effects of different degrees. Some researches prove that about 25% of renal failure is related to renal toxicity of the drugs.
Only after fully understanding the causes of ESRD, can we effectively prevent it and reduce its harms.

Then, how to prevent ESRD? Pay attention to the following four aspects in order to prevent ESRD:

1. Prevent the occurrence of diseases leading to renal dysfunction and if these diseases had occurred, put their deterioration under strict control and closely monitor renal functions. The clearance rate of creatine, which is the most sensitive index of kidney disease, should be examined once every 3 to 6 months.
2. Protect the kidney. Health physical examinations should be done once every half or one year and the examination items should include renal functions (blood creatinine, urea nitrogen and clearance rate of creatinine), B ultrasound, and urine analysis and so on.
3. Nowadays, patients with Uremia do not attach enough importance to the early treatments, and as a result, many of them lose the best opportunity of treatment. Positive formal traditional Chinese medicine treatment should be recommended, because it can enhance the compensatory effects of other organs on renal function, ease the burden of kidney and promote the recovery of damaged renal function. Through that, patients with early Uremia can keep their renal functions within a normal range for a long time.

4. Avoid taking medicines with renal toxic. For more information, please Email us at khkpcn@hotmail.com

Effective Measures to Prevent Diabetic Nephropathy (Diabetic Kidney Disease)

The early prevention of Diabetic Nephropathy (Diabetic Kidney Disease) is very important and the common prevention measures are as follows:
1. Patients who have suffered from diabetes for more than 5 years should regularly check up the renal functions, the nature determination of urine protein, the ration of 24-hour urine protein and examine the blood pressure and the ocular fundus.
2. If the condition is allowed, examinations of urine microalbumin and β2-microglobulin should be done to diagnose the diabetic nephropathy as early as possible. If the urine microalbumin increases, detections should be done for 3 times in a row within 3 to 6 months to make sure whether it is persistent microalbumin urine or not.
3. If the increase of microalbumin is determined and there is no other cause to its increase such as urinary tract infection, exercises and primary hypertension, the patients must be alert to this phenomenon and should try to control the blood sugar to make it close to the normal level. Meanwhile, on the aspect of diet, low-salt and low-protein food and high-grade protein are preferred.
In addition, patients should receive the guidance from standard physicians to treat their disease. In recent years, a lot of scholars have made discussions to the cause and mechanism of this disease and they have reached the following consensus: the causes of chronic kidney disease (CKD) are that immune complex deposits in the glomerulus, immune hyperfunction results in deficiency-excess complications.

Treatment in combination with dialectics: reducing phlegm as the main way and tonifying liver and kidney or recuperating spleen and kidney as the assistant way in the early period; promoting blood circulation and removing obstruction in channels together with recuperating blood and expelling toxins in the middle period; in the later period, expelling toxins, consolidating and protecting the stomach and dealing with various complications well. For more information, please Email us at khkpcn@hotmail.com

Stem Cell Transplantation Treats Lupus Nephritis

Lupus Nephritis is immunity Damage refers to Systemic Lupus Erythematosus (SLE) combined with bilateral kidney damage. One of the main death reasons of SLE patients is the Kidney Failure. The traditional treatment for Lupus Nephritis makes disease repeat again and again, but the occurrence of stem cell transplantation technology brings new hope to the patient.
The necessary condition of Stem Cell Transplantation treats Lupus Mephritis
1. The pretreatment before transplantation
This is a measure which let the receptor receive extraneous hemopoiesis and reduce the burden of cancer cell; the classical plan is having cyclophosphamide 60 mg/kg for 3 days, and adding 8~12 gray for STBD or FEBI.
2. Receptor and supplier should have the matching human HLA system
It exists in sixth pair of chromosome, doctor call this HLA-A,B,C,DR locus, ,HLA—DR locus related to whether transplantation can success, they must be match. In this way, it has high success chance and low risk.
3. Need a certain amount of hematopoietic number
This is not difficult to understand, since as seed cell, it will go to the new “soil” environment to take root, sprout, bloom and bear fruit, it is not a smooth sailing. In the process will be lost some stem cells, and can’t work without a certain quantity of stem cell.
The process of Stem Cell Transplantation treats Lupus Nephritis
First let largely hemopoiesis of marrow are released into blood; this process is called “mobilization”. Then through the blood cells centrifuges separate a lot of blood for transplantation, this is called “peripheral blood transplantation”. At present, people who donate marrow don’t need to extract marrow, just “donate blood”. Furthermore, with the development of technology, now using the technology of hemopoiesis “mobilization”, only need gather 50-200ml separated peripheral blood for getting a sufficient number of hemopoiesis. After gathering enough hemopoiesis, the blood can go back to the patient’s body.
The effect of Stem Cell Transplantation treats Lupus Nephritis
The treatment of Stem Cell Transplantation for Lupus Nephritis doesn’t have any side effect, because Stem Cell Transplantation has the function of rebuilding the damaged immune system, so the treatment of Stem Cell Transplantation for Lupus Nephritis can make patient avoid disease relapse, then achieve the purpose of treating Lupus Nephritis fundamentally.

A lot of clinical research has proved that the treatment of Stem Cell Transplantation for Lupus Nephritis has effective effect, which blocks renal fibrosis fundamentally, and repair the function of damaged renal cell; this is the best method to treat Lupus Nephritis. For more information, please Email us at khkpcn@hotmail.com

Reduce Creatinine for Chronic Renal Failure by Stem Cells and Micro-Chinese Medicine

Clinically, for Kidney Disease patients with light symptoms, they should take Coated Aldehyde Oxystarch or Shen Shuanning orally; some patients use mannitol salt preparations or Chinese medicine enema. In a short time, these symptomatic treatment methods have lowered indexes, but with the development of illness condition, the creatintine will occur repeatedly. How to reduce creatintine and clear toxin substance?

The regular treatment principle of Western Medicine for Chronic Renal Failure (CRF)

1. Anemia Patients should replenish chalybeate, folic acid, rebuild human erythropoietin. For hemoglobin is lower than 60g/L, patients should be transfused a small amount of blood for several times. Patient with Neuromuscular Disease can replenish nutrition and vitamin D3; external emulsified oil can be used for skin problem, at the same time, take antihistaminics orally and control phosphorus intake.

2. The treatment of CRF should mainly pay more attention to treat primary disease and correct the reversible factors.

3. The treatment of Cardiovascular Complication: the usage of hypotensor is the same as the ordinary High Blood Pressure Disease, furosemidum has a good effect among diuretics. Uremic Pericarditis is likely to be improved after the positive dialysis.

4 Besides the normal medicine treatment, the diet treatment for CRF can’t be neglected; limit protein; patients should have O.6g/kg high quality protein every day, and regulate them on the basis of GFR. If GFR≤5ml/min, the daily protein intake should reduce to 20 g and add amino-acid therapy, general usage 0.1~0.2g amino acid, and take them orally by 3 times a day or use slow static drops one time.

5. Correct the imbalance of water, electrolyte and acid-base: sodium salt intake decrease as well as GFR, if patients present Hyponatremia and Hypernatronemia, they should limit or replenish water. Hyperkalemia patient present 6.5mmol/L potassium, they need to be treated immediately.

Micro-Chinese Medicine Osmotherapy has special effect for treating Chronic Renal Failure. The pure Chinese medicine can promote the blood circulation by expanding all levels of renal arteries, alleviating “three high” state of glomerulus, repairing glomerular basement membrane, promoting metabolite such as toxin etc. to discharge from body, improving the symptom of high blood pressure and metabolic acidosis, thus the adverse symptoms of nausea will disappear, such as nausea, vomit etc; the active Chinese medicine will go into the renal lesion rapidly, which will closely connect with various pathogenic factors such as immune complex, nephritoxic factor etc, then attacking, breaking, dissociating and clearing these pathogenic factors with strong power, blocking the continuous deterioration of kidney.
In addition, the active substance of Chinese medicine has powerful repair function, which supplies renal needed substance, such as amino acid, protein etc, thus recovering the damaged function nephron, repairing the damaged renal inherent cells, restoring the metabolism function gradually, so as to reduce creatinine fundamentally and achieve the effect of non-recurrence.

Stem cells refer to those cells that are not mature and haven’t differentiated yet; they can renew themselves with a high degree of proliferation and potentials to develop into multi-lineage cell groups and further develop into different complicated organs. So what are the characteristics advantageous of stem cells, and which factors affect the curative effect of Stem Cells Transplant?
Stem cells can be divided into several kinds: 1. Topipotent; 2. Pluripotent; 3. Multipotent. Pluripotent will develop and grow to become multipotent gradually, but multipotent can only develop into one certain kind of cells in a certain organ (to maintain the self-renewal of a specific histiocyte; such as colorectal crypt cells).
Characteristics of stem cells: 1. stem cells keep its undifferentiated or low-differentiated situations all their lives; 2. number and position of stem cells in organism remain relatively unchanged; 3. stem cells have the ability to self-renew and unlimited proliferation; 4. stem cells have the potentials of multi-lineage, which can differentiate into different kinds of histiocytes; 5. stem cells can either proliferate for consecutive generations or remain resting state for a long period of time; 6. stem cells have activated factors which can activate the dormanting cells and maximize their effect to keep the health situation at its best level.


Therefore, the main function of Micro-Chinese Medicine Osmotherapy is reapir+block, the main function of Stem Cells Transplant is rebuild. The two combined treatment have a significant effect for Chronic Renal Failure. For more information, please Email us at khkpcn@hotmail.com

Early Symptoms of ESRD

The symptoms of Uremia present in every system, such as the nervous system, digestive system and so on. Uremia is the later symptom of all kinds of Kidney Disease. The occurrence of these symptoms seriously threatens patient’s physical and psychological health. What are symptoms of early ESRD?
Because metabolic acidosis, fluid and electrolyte imbalance and other factors lead to patients present various kinds of symptoms which are more complicated, these symptoms including anemia, nausea and vomiting, bleeding tendency, high blood pressure etc. These symptoms can be shown in all systems; in the following is the symptom of ESRD:
1. The symptom of the nervous system: the symptom of this system is the main symptom of Uremia. Patients may appear dizziness, headache, lacking in strength, understanding and memory diminished, and other symptoms. Patients even appear dysphorie, muscle quiver, hyperspasmia, apathetic facial expressions, drowsiness and coma etc.
2. The symptom of the digestive system: this is the most early and prominent symptom. Such as inappetence, dyspepsia, anorexia, nausea, sickness, diarrhea etc.
3. The symptom of cardiovascular system: patients more appear heart failure, arrhythmia, myocardial damaged, aseptic pericarditis and other complications, patients appear precordialgia.
4. The symptom of respiratory system: patients have kussmaul breath which is slowly and deeply. The Uremia patient’s breath usually accompanied with urine flavour, patient with seriou Uremia appear pulmonary edema, fibrinouspleurisy or calcificationpulmonum and other lesions.
5. The symptom of skin: Uremia patients always have the symptom of skin itch, in addition, patients appear dry skin, desquamation, the color of skin is yellowish-brown, and we can see white crystal in sweat glands mouth of skin.
6. Material metabolic disorders
(1) Glucose tolerance reduces; patients more appear Diabetes symptom of “three more one less”.
(2) Negative nitrogen balance: this will cause patients slim down, Cachexia and Hypoalbuminema.
(3) Hyperlipemia

Many patients care about the treatment of ESRD, and we advice patients use Micro-Chinese Medicine Osmotherapy + Stem Cells Transplant to alleviate all symptoms of kidney disease. For more information, please Email us at khkpcn@hotmail.com

The Clinical Manifestation of Diabetic Nephropathy

It is known to all that Diabetic Nephropathy is a terrible disease, but what is the presentation of Diabetic Nephropathy? In order to keep a good health for you and you family, and for patients who are in the edge of Diabetic Nephropathy, while they are still don’t know, we can talk something about the clinical manifestation of Diabetic Nephropathy.
The first clinical manifestation of Diabetic Nephropathy is proteinuria.
Patients don’t have clinical protein in the early stage of Diabetic Nephropathy, only the radiation immune method can detect the micro-proteinuria. Proteinuria is the only clinical manifestation in the early stage of Diabetic Nephropathy, proteinuria will develop from intermittent to persistent gradually.
The second clinical manifestation of Diabetic Nephripathy is edema. Normally there is no edema in the early stage of Diabetic Nephropathy, a few of patients will appear the mild edema before reducing the plasma protein. The later period expression of Diabetic Nephropathy is that if it has a large number of proteinuria, the plasma protein is very low, the edema will aggravate gradually.
The third clinical manifestation of Diabetic Nepropathy is high blood pressure. The morbidity rate of Type 1 Diabetes patients who don’t have kidney disease will not increase, and Type 2 Diabetes patients who always accompanying with high blood pressure, and high blood pressure rise with proteinuria.
The fourth clinical manifestation of Diabetic Nephropathy is Kidney Failure. The development of Diabetic Nephropathy is very different. For some of the people with the mild proteinuria will continue for a long time, but the renal function is normal, and some patients have few urine protein, which can develop into the Nephrotic Syndrome quickly, the renal function deteriorate gradually, even develop into Uremia.
The fifth clinical manifestation of Diabetic Nephropathy is anemia. Patients with obvious azotemia, maybe he has mild anemia.

The sixth clinical manifestation of Diabetic Nephropathy is the complication of the others visceral organ, such as heart failure, myocardial infarction, diabetic neuropathy, and diabetic retinopathy. For more information, please Email us at khkpcn@hotmail.com

How to Define My Stage of Diabetic Nephropathy (Diabetic Kidney Disease)

Diabetic Nephropathy is a Chronic Kidney Disease which is caused by Diabetes. Diabetic Nephropathy is one of the most frequent and dangerous complications of Diabetes. This disease is featured by slow development and without obvious symptoms in the process of attacking. The first phase of the disease does not cause any discomfort, so often a doctor has already treated in the last stages of Diabetic Nephropathy, it is more dangerous for patients in the last stages. Therefore, timely investigate and detect of early signs of Diabetic Nephropathy is an so important task.
Teach you how to distinguish five main stages of Diabetic Nephropathy:
Stage 1 – The early stage of Diabetes
This stage is characterized by an increase in GFR (Glomerular Filtration Rate) of more than 140 ml / min, an increase in renal blood flow.
Stage 2 – the onset of Diabetes is no more than 5 years.
In this stage, renal tissues begin to present the initial change. This stage is characterized by increasing GFR (Glomerular Filtration Rate) and thickening of basement membranes.
Stage 3 – The Diabetes history is between 5-15 years.
This state is characterized by periodicity high blood pressure or normal GFR.
Sage 4 –severe Diabetic Nephropathy
This stage is characterized by normal or reduced Glomerular Filtration Rate, Hypertension and Proteinuria.
Stage 5– Uremia (Diabetes history is more than 20 years)
This stage is characterized by decreased Glomerular Filtration Rate, and arterial hypertension. In this stage, the person present the symptoms of intoxication.

It is very important to identify the development Diabetic Nephropathy in the first three stages, when treatment is still possible to change. For more information, please Email us at khkpcn@hotmail.com

What are the Causes of Diabetic Nephropathy (Diabetic Kidney Disease)

The primary cause of Diabetic Nephropathy (Diabetic Kidney Disease) is decompensation of Diabetes – Long-term hyperglycemia. Consequence of hyperglycemia is high blood pressure, which also affects the kidneys. With the high sugar and high blood pressure, which are easy to give rise to the Renal Insufficiency, at the same time, the toxic substances which are discharged by kidney begin to accumulate in the kidney, and then give rise to toxic symptoms of kidney.
Each kidney is made of hundreds of thousands of filtering units called Nephrons. Each Nephron has a cluster of tiny blood vessels called a Glomerulus. These structures work together to remove waste from the body. Too much blood sugar can damage these structures, cause them become more and more thick and get other damage. Slowly, over time, more and more blood vessels are destroyed. The kidney structures begin to leak and protein (albumin) begins to pass into the urine.
Diabetes patients are easy to suffer from DN if they have the following conditions:
African American, Hispanic, or American Indian origin
Family history of kidney disease or high blood pressure
Poor control of blood pressure
Poor control of blood sugars
Suffer from Type 1 Diabetes before age 20
Smoking

Diabetic Nephropathy generally goes along with other diabetes complications including high blood pressure, retinopathy, and blood vessel changes. For more information, please Email us at khkpcn@hotmail.com

Can Lupus Nephritis Female Patient Get Pregnant

Can Lupus Nephritis female patients get pregnant? If Lupus and immuno-serological test show abnormal, the urine test and renal biopsy reflect the glomerulus are normal or light pathological changes, non-steroidal anti-inflammatory can be used to improve the symptoms. Almost every married young woman wants to be a mother, especially for Lupus Nephritis female patients.

What kinds of Lupus Nephritis female patients can get pregnant? In the previous time, people thought that pregnancy will cause the recurrence and deterioration of Lupus Nephritis, so they advocate Lupus Nephritis female patients avoid getting pregnancy. But in recent years, a lot of materials have proved that: if lupus nephritis without unexplained fever in a year, without multiple arthritis, no facial butterfly- rash, the blood pressure normal, every month the urine will test 12 times without cells and proteinuria; the kidney function is normal, various serological examination turn negative, stop taking cytotoxic medicines (such as cyclophosphamide, etc) over one year, pregnancy will have no influence to mother and fetus. Pregnancy does not increase the reanimate rate for the Lupus Nephritis Patient, and pregnancy has little effect for long-term prognosis of lupus nephritis. Next, the patient should keep physical and mental peaceful, have a good appetite, with a lot of energy, have a rapid reaction, although these are not mandatory index, also be the necessary conditions to get pregnant, and be the important factors to keep the conception quality. With the above conditions, if the Lupus Nephritis female patients want to get pregnant, she must get the urological medical with doctor’s agreement, under the guidance of urological medical doctor and gynecologist, the patient could get pregnant. Because Lupus Nephritis could damage the vessels of whole body, include placenta and uterus’s vessels.

If Lupus Nephritis active in the period of pregnancy, it will cause dead fetus and placenta stripping early. The latter one will cause the massive haemorrhage which will lead to the death of pregnant woman. So when the Lupus Nephritis patients get pregnant, they should have a physical examination twice every month in the period of pregnancy, the whole period of pregnancy and after delivery two month, the patient should in the closely guardianship of doctor, in case of Lupus moving, and the patient couldn’t get the treatment in time. Some scholars believe that once the patient gets pregnant, they should take 20 mg prednisone every second day until 8 weeks after delivery, because this will reduce the active chance of Lupus.


In addition, Micro-Chinese Medicine Osmotherapy + Stem Cells Transplant can be used for young Lupus Nephritis female patients, which can get the significant effect and help them to deliver the healthy babies. For more information, please Email us at khkpcn@hotmail.com

The Impacted Factors of Changing Diabetes into ESRD

1.Genetics
People have known that the occurrence of Diabetic Nephropathy is related to genetics for ages. The occurrence rate and degree of severity are different for different racial DN patients, and that means the same family has high morbidity, and some families suffer most even in the same ethnic group. Clinically, we usually find that DN still occurs in some diabetic sufferers with reasonably controlled blood sugar meanwhile some diabetic sufferers with unreasonably controlled blood sugar do not suffer from DN at all. That partly illustrate that the occurrence of Diabetic Nephropathy is highly related with genetics.

2.Hyperglycemia(high blood sugar)
A 1985 report from the WHO DN research group revealed that DN is common in people whose fasting blood glucose is >7.8mmol/L. High glucose, which is the feature of Diabetes, leading to a series of metabolic disturbance is the main cause of Uremia. After long-term increased blood glucose, renal tissue proteins react with molecules of glucose, which leading to altered biochemical structure of the protein and eventually the occurrence of proteinuria. Strict control over blood glucose on Type 1 and Type 2 Diabetic sufferers can delay the occurrence of micro-albuminuria and curb the process of leading to clinical proteinuria.

3. Hypertension (high blood pressure)
High blood pressure which accelerates the development of DN and undermines renal function is also a main cause of DN, even causes uremia. Most high blood pressure is secondary to Type 1 Diabetes, but for Type 2 Diabetes, high blood pressure occurs before Diabetes.


However, there is one thing in common that hypertension make Diabetes deteriorate, so carefully control over blood pressure is necessary, especially for sufferers afflicted by Type 1 Diabetes, if effective measures of controlling blood pressure have been taken in the early stage of DN, the occurrence of uremia can be delayed for 10 to 20 years.

63 Years Old with PKD on Dialysis Chinese Medicine Treatment

"My 63 years old mother is suffering from pkd and she is on dialysis for last 3 years. Could you please provide suggestions on Chinese medicine treatment for her disease?"

This is Dr. Lydia from Kidney Disease Hospital in China, you have ever consulted us about your mother's PKD on our website, so how is her condition now?

For patients with PKD, the enlarging of the cysts will press the around kidney tissues and cause lack of blood and oxygen supply in the kidneys. That's why the kidney function is damaged. If we dilate the blood vessels, improve the microcirculation on the cysts walls, the cyst liquid can be reabsorbed and discharged out with blood circulation gradually. So the cysts can be shrunk and the kidney function will be better. So early treatment is very important to stop the progressing of the disease and improve the kidney function.


Our hospital is specialized in treating kidney disease and we treated many patients similar to her condition. And our main treatment is TCM, it can not only discharge the toxins in body and shrink renal cytes, but also can repair renal cells and improve renal function. If the patient cooperate with our doctors, it is very hopeful to prolong dialysis, even get rid of dialysis. I hope you can send me her latest test reports including urine test, blood test, renal function test and ultrasound. I will analyze it and give you specific advice. any question, feel free to Email us at khkpcn@hotmail.com

CKD on Dialysis with GFR 10 How to Avoid Kidney Transplant

If CKD on Dialysis with GFR 10 patients want to avoid kidney transplant, we will first suggest you the unique traditional Chinese medicines Osmotherapy. It is a natural herbal therapy applied externally on acupoint of lower back (kidney area). Herbal bags containing dozens of herbal medicines are soaked previously in penetrants, and then placed on the lower back part. With the help of osmosis device, effective ingredients of herbal medicines will infiltrate into kidneys through the main and channels. There is no pain, and it is kind of like a massage.

Besides, we will suggest patient to have the acupuncture, herbal bath,moxibustion , oral take herbal medicines etc. Those treating therpay combined together can have the improving blood circulation, anti-inflammation, dilating blood vessels, anti-coagulation and degradation etc.

There are 3 stages in the kidney failure. Inflammation stages, fibrosis stage and scarring stages. when the kidney cells in the first 2 stages, it is damaged but still have some function. when have some herbal treatment, it can be improved. when the kidney cells in the scarring stage, treatment can not work on that. We think CKD on Dialysis with GFR 10 patients still have great chance to improve kidney function and avoid dialysis.

They can treat stem cell treatment as the additional treatment. I think just from the treatment above, your kidney condition can also be improved. if you have long term run, you can have stem cell treatment. stem cells can differentiate into kidney cells. Stem cells are original cells with multi-potential and multi-directional differentiation ability, which means that, after cultivation, stem cells can differentiate into functional cells of one specific organ, like the kidney. We take advantage of this very characteristic of stem cell in treating kidney function decline. Umbilical Mesenchymal Stem Cells Transplant and Cord Blood Stem Cell Transplant are adopted in our hospital, and they mainly differentiate into kidney parenchymal cells and kidney blood capillary cells separately.

Stem cells are provided and cultivated by the hospital, and transfused into patient’s body through intravenous drip. So, no surgical operation is needed.

Before you have stem cell treatment, we must have the treatment above to help you clean the internal environment, thus we can guratee the cells can work well in the body.


In summary, this treatment is a conservative treatment method, and aims at protecting and restoring overall kidney function to a more satisfying level to prolong or avoid the necessity of dialysis or kidney transplant. For more information, please Email us at khkpcn@hotmail.com

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