Does Renal Failure Affect Serum Creatinine Levels

Serum creatinine levels display a patient's kidney function. Normal value of serum creatinine level differs from one hospital protocol to another but it is around 0.6 to 1.2 mg/dL in general. People with different stages of Renal Failure usually have higher than normal serum creatinine levels.

Renal Failure is a general term indicating kidney dysfunction instead of a specific disease. It is a critical state caused by known or unknown diseases or factors. It results the kidney failing to remove waste and toxins from blood. Dysfunction of kidney can be represented by increasing serum creatinine levels.

Serum creatinine level measures the kidney excretory ability of cleansing toxins and waste from blood. Ordinarily, our kidneys work flawlessly to remove most toxins and waste from blood and then discharge them through urination. Therefore, the measurement of serum creatinine level is about 0.6 to 1.2mg/dL for the healthy people or mild Renal Failure patients.

Each kidney contains about more than 1 million to 2 millions nephrons. They are the basic functional unit of the kidney. They filtrate our blood and regulate fluid and electrolytes as well as acid-base balance of our bodies. Glomerulus, the small but significant part of a nephron is responsible for filtrating blood. If the glomeruli are damaged, toxins and waste will be left and gathered in bloodstream. Because each people have millions of nephrons only a few amount of glomerular damage may not be detected by serum creatinine level. That is to say, mild glomerular damage will not cause serum creatinine levels to go up. Whenever a Renal Failure patient's Serum Creatinine level increases, about at least 50% of glomerulus are destroyed. In a word, Renal Failure dose affect serum creatinine levels to increase without timely effective treatment.

Renal Failure patients with increased serum creatinine levels usually have one or some symptoms of Renal Failure, such as water retention, internal bleeding, and abnormal urination and so on. Further progression of Renal Failure may bring about more serious health problems. Patients with Renal Failure should treat increasing serum creatinine levels seriously because they imply more damage of glomeruli and worsening of kidney function. Please refer to 'How Immunotherapy Helps Reduce High Creatinine Levels' for more helpful information about treatment.