Name: LiYun
Sex: Woman
Nationality: Jiangxi, China
Process of diagnosis and treatment: She got bellyache, diarrhoea and
arthralgia ten years ago. One week later, there appeared red spots not beyond
skin on leg inside. Then she hospitalized in Jiangxi. She was diagnosed with
Purpura Nephritis and received glucocorticoid treatment. However, she was not
satisfied with the treatment. Six years ago, she felt overall weakness so that
she went for a test in the local health center. The test result showed that both
urine protein and occult blood were positive. It had no effects on her to use
penicillin then she began to take prednisone 20 mg one day. Two months later
after taking prednisone, protein urine and occult blood became negative. From
then on, the dose of prednisone was reduced to 2.5 mg one day and half year
later she stopped taking medicines. The test result showed that protein +++
occult blood +++ and there appeared red pot on the leg inside without obvious
inducements. She came to Shijiazhuang Kidney Hospital Disease for further
treatment.
Admission condition: After hospitalizing here, the test result is 24h protein
urine is 2.13g/d, urine protein + + +， Urine creatinine( UCR )
7840.322umol/l，triglyeride ( TGL)4.68mmol/l，ultrasound examination shows that
the size of right kidney is 10.5cm, left 10.7cm. ECT indicates that GFR is
104ml/min. During hospitalizing here, Stem Cell Transplantation is performed on
her. When she leaves hospital, symptoms are normal. Appetite, sleep and urine
are normal. Protein and occult blood becomes negative. Creatinine clearance is
elevated.
Experts comment: People with Purpura Nephritis have normal kidney function.
Stem cells are taken from cord blood without any antigen on the surface. When
transplanted into body, stem cells will move to kidney nidus to directly repair
worn or damaged intrinsic cells protect residual cells. There are no side
effects in the process of stem cell transplant to achieve the goal of treating
Purpura Nephritis fundamentally.