A New Treatment of Lupus Nephritis - Stem Cell Transplantation

Lupus Nephritis is the most serious complication of systemic lupus erythematosus (SLE). Main cause of death in Lupus Nephritis patients is Renal Failure. Conventional therapies for Lupus Nephritis are often unable to control the progression of nephritis. A new therapy for Lupus Nephritis -Stem Cell Transplantation appears.
Pre-Stem Cell Transplantation
Pretreatment before Stem Cell Transplantation is performed: Pretreatment aims to make receptor receive hemapoiesis and reduce the burden of cancer cell.
Both receptor and donor have the matching Human Leucocyte Antigen( HLA)
There must be a large of hemapoiesis: It is not difficult to understand. As seed cells, stem cells need suitable soil to plan, grow, flower and fruit. The process of growth is not smooth during which there must be stem cell dying. So a large of stem cells is needed.
The process of Stem Cell Transplantation for Lupus Nephritis
Firstly, hemapoiesis in Bone marrow is released into blood and then a large of hemapoiesis is gained by the blood cell separator. With technology developing, we only need to collect 50-200mg Peripheral Blood which can provide enough hemapoiesis.
Effects of Stem Cell Transplantation for Lupus Nephritis
There are no side effects by Stem Cell Transplantation. Due to the reconstruction of immune system, stem cells treating Lupus Nephritis is able to avoid recurring of the condition achieving the goal of treating Lupus Nephritis fundamentally.A number of clinical trails show that Stem Cell Transplantation for Lupus Nephritis has good curative effects which can fundamentally block renal fibrosis and repair damaged renal cells. At present, Stem Cell Transplantation is the best approach to treat Lupus Nephritis.

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