IgA Nephropathy is a kind of glomerular disease which has features of
mesangial proliferation and prominent sedimentation of IgA in the mesangial
area, IgA Nephropathy is common in kids and youngsters, the number of male
suffering this kind of disease is two times than that of female. Infection of
upper respiratory tract is the most common reason for morbidity of IgA kidney
disease; sometimes diarrhea and urinary infection can also induce IgA
Nephropathy. What are the symptoms of IgA Nephropathy? The answers are as
follows:
Clinically, the symptoms of pediatric IgA Nephropathy are various, first
hematuria is the most common one.
Hematuria which can be seen merely through microscopic examination, patients
present symptoms when the patients are attacking by the disease. Here it is
worth to point out that these symptoms can be interconverted.
Generally, hematuria which can be seen by naked eyes, this is the first
symptom for 80% of pediatric patients with IgA Nephropathy. North American and
European suffer higher morbidity than Asian. This is a disease which is commonly
related to infection of upper respiratory tract (Berger disease), And usually
after 24 to 72 hours of infection of upper respiratory tract the hematuria
occurs, Occasionally occurs several hours later and most kids suffer from
antiadoncus simultaneously, but after tonsillectomy most pediatric patients can
be curbed.
Among other things, some pediatric patients have the symptoms of hematuria
and proteinuria. At this point, hematuria can either be observed by naked eyes
or by microscopic examination. Proteinuria is commonly in light and medium
level.15% to 30% patients with IgA Nephropathy has the expression of the kidney
disease syndrome.
Apart from the symptom of hematuria, pediatric patients with IgA kidney
disease also have the symptom of hypertension and kidney insufficiency.
Hypertension are most common in adults which represent 20%, and kids represent
only 5%.Hypertension is an prominent sign that the state of kidney disease
deteriorates and most of patients’ renal function deteriorate swiftly. Less than
5% of patients with IgA Nephropathy have performance of acute kidney
disease.
Elder kids repeated hematuria which can be seen by naked eyes are usually
accompanied by infection of upper respiratory tract, in this situation IgA
Nephropathy should be considered. Hematuria merely diagnosed by microscopic
examination or hematuria which can be seen by naked eyes accompanied by
proteinuria, it probably means that IgA Nephropathy exists.
Thus, pediatric patients should take biopsy as soon as possible. The symptoms
of Nephrotic syndrome, acute nephritic syndrome, hypertension accompanied with
kidney dysfunction may probably indicate that the patient is suffering from IgA
Nephropathy. Meanwhile patients should pay more attention to other diseases
which causing IgA sedimentation in mesangial area. For more information, please
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