Stem Cell Therapy in Shijiazhuang Kidney Disease Hospital Two

Kidney diseases that can be treated by Stem Cell Transplant in Shijiazhuang Kidney Disease Hospital:
2. Rapidly Progressive Glomerulonephritis
A scientist used autogenous hemopoietic stem cell transplant treated a mouse with Crescentic Glomerulonephritis. After transplant, the survival rate of that mouse increased remarkably; the levels of dsDNA Ab, ssDNA and antoneutrophil cytoplasmic also decreased. Hematuria, proteinuria and peripheral lymph node enlargement also alleviated. Deposition of fibrin decreased and formation of crescent also inhibited. From this experiment we can see how powerful the Stem Cell Transplant is in treating Glomerulonephritis.
3. Diabetic Nephropathy
Kidney damage is a common complication of Diabetes. Diabetes leads renal microcirculation obstructed resulting in oxygen and blood insufficiency of the kidney, damage of renal intrinsic cells and proteinuria. Loss of massive proteins leads to Hypoalbuminemia which decreases oncotic pressure of plasma and causing edema. Damaged renal intrinsic cells fail to regulate fluid and electrolytes normally causing water and sodium retention and as a consequence, edema appears. In this case, treating of Diabetic Nephropathy should focus on repairing damaged renal intrinsic cells and preventing further deterioration of the kidney. Diabetic Nephropathy happens in relation to many factors such as Hyperglycemia, abnormal hemodynamics of the kidneys as well as familial heredity.

Either primary or secondary causes cause blood glucose elevating which change renal hemodynamics. Then, elevated glomerular perfusion and filtration increases the pressure to the glomerular capillaries hurting renal intrinsic cells. That broadening of mesangium; fusion of epithelial cell foot processes and formation of dense droplets detaching glomerular epithelial cells from glomeruli therefore thickens glomerular basement membrane and eventually, diffuse mesangium, nodular lesions activate the process of Kidney Fibrosis leading to glomerular sclerosis. According to this, preventing or delaying development of Diabetic Nephropathy is very important to reduce the morbidity rate of Diabetes. Stem Cell Transplant can increase the actual number of functional renal intrinsic cells thus improving kidney function and making the patients lives normally. (To be continued)

Stem Cell Therapy in Shijiazhuang Kidney Disease Hospital One

Stem Cell Therapy is no longer a new technique for people all over the world. Treating kidney diseases by Stem Cell Therapy have been practiced clinically. Stem cells are known as Universal cells because they have the superpower to differentiate into various cells of tissues and organs of the human body. Stem cells are a group of undifferentiated cells that can be cultured in vitro and then be directed to differentiate certain cells. Stem cell therapy provides a new and promised treatment for patients with kidney diseases.
In China, with the support of government development of Stem cells in treating kidney disease improves day by day. In 2010, the first Stem Cell Centre for kidney disease was founded in Shijiazhuang, the capital city of Hebei Province, China. This Stem Cell Centre is authorized to do studies of stem cells in the nephrology field and practice clinically. This centre belongs to Shijiazhuang Kidney Disease Hospital. So, what are those kidney diseases can be treated by Stem Cell Transplant in Shijiazhuang Kidney Disease Hospital?
In Shijiazhuang Kidney Disease Hospital, cord blood stem cells are the most common stem cells that applied clinically. Besides, cord blood stem cells have close relationship with kidney disease. Cord blood stem cells are easy to be separated; their proliferation ability is very considerable; and they have very low immunogenicity that rejection almost will not happen. In Shijiazhuang Kidney Disease, Stem Cell Transplant is applied to treat the following kidney diseases:
The principle of treating IgA Nephropathy by stem cell transplant is that, variant stem cells can inhibit the production of autoactive T cells which decrease the production of IgA antibodies.
1. IgA Nephropathy

Pathogenesis of IgA Nephropathy is not yet figured out at present. There are some experiments shows disturbing immune system plays an important role in the development of IgA Nephropathy. Many medical scholars believe that IgA antibodies are not antigen-dependent. They think IgA Nephropathy is a kind of stem cell disease. For patients with IgA Nephropathy, abnormal increased levels of autoactive T cells are found. Peripheral blood increase excessive IgA antibodies are also detected. Professor Sakai used variant bone marrow stem cells treating a patient with both leukemia and IgA Nephropathy. After variant bone marrow stem cells transplant, leukemia was treated and deposition of IgA immune complex in mesangial area of kidney also disappeared. The principle of treating IgA Nephropathy by stem cell transplant is that, variant stem cells can inhibit the production of autoactive T cells which decrease the production of IgA antibodies. (To be continued)

What do Stem Cells do after infusing in the body of patient with kidney disease

Stem cells are a group of undifferentiated cells that are able to replicate, proliferate and differentiate into various cells in the body by themselves. They are the original cells that further form all types of tissues and organs of our bodies. They can be directed to differentiate into any type of cells in some certain conditions. Stem cells are recognized and accepted as universal cells by many medical scholars.
Recent years, more and more successful cases of Stem Cell Transplant in treating various diseases are reported by many countries. Stem cells also can be used to treat kidney diseases. They are found out that can differentiate into any renal intrinsic cells. These years, stem cells are practiced clinically to treat kidney disease. Well then, what does Stem Cells Transplant do after infusing into the body of patient’s’ with kidney diseases? A nephrologist from Shijiazhuang Kidney Disease Hospital listed the following actions of stem cells after infusing into the body of patient’s with kidney diseases:
1. Differentiating into damaged tissue cells of the kidney;
2. Replacing the function of damaged renal intrinsic cells;
3. And stimulating reproduction function of the body to proliferate more renal intrinsic cells.
Many people worrying about the side effects of Stem Cell Transplant. What are the side effects of Stem Cell Transplant? Until now, there are no side effects that documented in Shijiazhuang Kidney Disease Hospital. Only a few patients are documented of having mild dizziness, headache and fever right after Stem Cell Transplant. However, such discomforts soon disappear. Stem Cell Transplant is expected to exhibit no side effects no matter Stem Cell Transplant delivered by any route. Nevertheless, no promise can be made that Stem Cell Transplant will not definitely produce any side effect.

Stem Cell Transplant is transplanting completely healthy stem cells into the patient’s body to achieve the goal of producing new functional cells and repairing damaged kidney function as well as stopping/delaying progression of kidney damage. If you want to know more information about stem cells, please continue to browse our website or sent emails to khkpcn@hotmail.com

Stem Cells Transplant:A Powerful Enemy of Kidney Diseases

At present, Stem Cell Transplant seems to be best solution in treating kidney diseases. What are the advantages and how does Stem Cells Transplant treat kidney diseases?
Principle of treating kidney diseases by Stem Cells Transplant:
Stem cells are able to proliferate unlimitedly. They can differentiate into various functional cells in the body. Besides, they have the same function after differentiate. In this case, stem cells can be used to repair certain damaged tissues or organs of the body. Stem cells are also able to differentiate into renal intrinsic cells thereby damaged kidney can be repaired and function normally again.
Advantages in treating kidney diseases:
1. Powerful reproductive ability and multi-directional differentiation ability of stem cells make stem cells differentiate into necessary renal inherent cells and reproduce spontaneously.
2. by cellular interaction and by producing cytokines to inhibit proliferation of T cells and their immune response. In this way, the recipients’ immune system will be “rebuild” and strengthened.
3. Supply of stem cells is good and convenient. Additionally, stem cells are easy to separate, culture, proliferate and purified. Stem cells still contain their characteristics even after multigenerational proliferation.
4. Stem cells have low immunogenicity. Stem cells are a group of undifferentiated cells which are hard to be recognized and rejected by our immune system. Rejection may not happen and Stem Cells Transplant needs no blood type match.
5. Stem cells that used in Shijiazhuang Kidney Disease Hospital are cultured to differentiate into renal inherent cells.

Because of these characteristics and advantages, stem cells are concerned by more countries in medical field. If you have any questions you can email to khkpcn@hotmail.com

Uremia: What Are the Damages of Long-term Dialysis

Uremia can produce some life-threatening complications to patients. To dealing with the threatening of Uremia, Dialysis seems to be a good intervention. Once their illness conditions are stabilized, they should be given standard treatments. Because without other standard treatment, Uremic patients may become dialysis-dependent and their kidney function will drop rapidly without other relevant treatment.
There are some damages may come out after long-term dialysis. Expert Zhanping Wang, from Shijiazhuang Kidney Disease Hospital introduced the following damages of long-term dialysis.
1. Infection
Patients with Uremia do not have enough immunity to resist infection. However, infection is a very common complication of long-term dialysis. Common infections are respiratory infection, urinary tract infection, pulmonary tuberculosis, renal tuberculosis and virus hepatitis.
2. Cardiovascular diseases
Cardiovascular disease occurs frequently on Uremic patients with long-term dialysis. Cardiovascular disease is also a significant cause of death. Normally seen cardiovascular diseases are Hypertension, Hypotension, Heart Failure, Dysrhythmia, Pericarditis, Coronary Ischemia and Myocardial Infarction.
3. Dialytic Osteopathy
Dialytic Osteopathy is caused be decreased kidney function of Vitamin D activation resulting in calcification insufficiency of osseous tissue. Dialytic Osteopathy usually manifests bone ache, fracture and myasthenia.
4. Anemia
Anemia is resulted by various problems of Uremic patients but the main reason of Uremic patients is because of kidney dysfunction. In addition, Uremic patients do not have good appetite so they eat a little and as a consequence, Anemia is aggravated.
5. Dialytic Encephalopathy
Dialytic Encephalopathy is also called Dialytic Dementia which is a complication of long-term Dialysis. In the early stage of Dialytic Encephalopathy, Uremic patients may exhibit intermittent difficult speeching and anarthria; later on they will get Motor Dysfunction, abnormal sensation, fibrillary, tremor and episodes of epilepsy.

Long-term Dialysis only is not a good choice for Uremic patients. The purpose of dialysis is to maintain the life of patient’s instead of making worse. Treating patients with Uremia should focus on preventing the process of Kidney Fibrosis and preventing continual damage of renal inherent cells. Email us if you have any problems regarding Uremia and other kidney diseases.

Is Purpura Nephritis Curable and How to Treat It with Stem Cells

Purpura, arthritis and abdominal pain will disappear spontaneously. Most people who have Schonlein-Henoch Purpura Nephritis for the first time can recover completely. Only a small part of patients will develop irreversible kidney disease due to touching allergen repeatedly. Once the kidney is damaged it is very difficult to recover entirely. Generally it has more chances to heal purpura nephritis if kidney damage occurs within one week or one month of the presence of purpura. Some will find kidney damage 2 years after purpura occurs. So people who have protein urine even hematuria should have regular tests for kidney function and routine urine for 1-2 months even much longer time. Some patients will recover completely. If they no longer touch the allergen, kidney function will be at the healthy state. But for some old people with Purpura Nephritis especially accompanied by hypertention or urine protein, it is difficult to make them recover completely. The kidney function will decline continuously. Many people may much concern about the treatment. Besides the conventional therapies, stem cells as an advanced technology, is used to treat Purpura Nephritis.

Stem cells are the cells capable of self-renewal and differentiation. Under the right condition, stem cells can differentiate into organ-cells of any type. Stem cells transplanted into body are able to produce healthy cells to repair and replace the damaged cells. Stem cells can regulate the immunologic mechanism, control purpura activity. The indicator of protein and occult blood will decline or become negative. In the long term it can repair the kidney intrinsic cells and block the kidney fibrosis. Presently, it has been used to treat purpura nephritis and has good effects. As the advanced technology stem cells has extraordinary promise and it is believed to have the potential to change the treatment of human disease.

The Newest Treatment for Lupus Nephritis – Stem Cell Therapy

Lupus nephritis is kidney damage which is a complication of Systemic Lupus Erythematosus. It is a disease accompanied with obvious manifestations of kidney damage. So it is the core of treatment to target kidney damage. Stem cell therapy has good effects on Lupus Nephritis which gives patients chances to get rid of the condition and improve their life quality.
Stem cells are a group of cells which have the ability to self-renew and differentiate into cells of any type to repair and replace the worn and damaged cells. Stem cells can regenerate endothelial cells of blood capillary of glomeruli and repair glomerular basement membrane to improve the GFR (Glomerular filtration rate). Stem cells also can obviously improve the symptoms like hypertention, edema, and changes in urine due to glomerular lesion.
Stem cells are able to differentiate into immune balance cells like Ts cells, Th cells etc that can remove these factors that can damage tubule, avoid the further tubule damage and prevent renal failure.
When transplant into body, stem cells will move to kidney with blood and then they are able to regenerate renal tubular epithelial cells and interstitial cells, repair damaged renal tubular epithelial cells and interstitial cells due to bacterium and germ and also enhance physical immunity to prevent renal failure. Stem cells can recover kidney reabsorption and excretion functions so that the goal of treating lupus nephritis can be achieved. In many cases, stem cell transplant has good effects on treating this disease.

Stem Cell Transplant as a brand new technology in medical world is believed to have the extraordinary promise on treating kidney disease. It is possible to improve life quality by stem cell transplant. New hope is in near future for people with Lupus Nephritis.